2-Phenyl-3,6-dimethylmorpholine

2-Phenyl-3,6-dimethylmorpholine is a drug with stimulant and anorectic effects, related to phenmetrazine.[1] Based on what is known from other phenylmorpholines with similar structure, it likely acts as a serotonin reuptake inhibitor and may produce antidepressant-like effects.

2-Phenyl-3,6-dimethylmorpholine

Legal status
Legal status	DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act
Identifiers
IUPAC name 2-phenyl-3,6-dimethylmorpholine
CAS Number	92902-99-3
PubChem CID	43174741
ChemSpider	38138973
CompTox Dashboard (EPA)	DTXSID20655677
Chemical and physical data
Formula	C12H17NO
Molar mass	191.274 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1NCC(C)OC1c2ccccc2
InChI InChI=1S/C12H17NO/c1-9-8-13-10(2)12(14-9)11-6-4-3-5-7-11/h3-7,9-10,12-13H,8H2,1-2H3 Key:FZEIVUHEODGHML-UHFFFAOYSA-N
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See also

• 3-Fluorophenmetrazine
• G-130 (2-Phenyl-5,5-dimethylmorpholine)
• 3,4-Phendimetrazine (2-Phenyl-3,4-dimethylmorpholine)
• PDM-35 (3,5-Phendimetrazine) (2-Phenyl-3,5-dimethylmorpholine)
• Manifaxine
• Radafaxine

References

1. DE patent 1143201, Siemer S, Doppstadt A, "Verfahren zur Herstellung von 2-Phenyl-3,6-dimethylmorpholine", granted 1963-02-07