Mexedrone

Mexedrone (also known as 4-MMC-MeO) is a stimulant and an entactogen drug of the cathinone class that has been sold online as a designer drug.[1][2][3][4] It is the alpha-methoxy derivative of Mephedrone.

Mexedrone
Legal status
Legal status
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
FormulaC12H17NO2
Molar mass207.273 g·mol−1
3D model (JSmol)

Pharmacology

Mexedrone acts as a weak serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with IC50 values of 5289 nM, 8869 nM and 6844 nM, respectively, as well as a weak serotonin releasing agent (SRA) with an EC50 value of 2525 nM.[5]

Mexedrone is illegal in Sweden as of January 26, 2016[6] as well as Japan as of August 24, 2016.[7]

gollark: SSDs/HDDs generally all support ECC anyway. There's none of this ridiculous feature gating in those.
gollark: `async function(username) { let result = await api.get('euw1', 'league.getLeagueEntriesForSummoner', 'MLR_5XD45pduq2iducsga00c4qi5sWqpaRkadd_E0fFhKXU') return result}` is a really longwinded way to write `api.get('euw1', 'league.getLeagueEntriesForSummoner', 'MLR_5XD45pduq2iducsga00c4qi5sWqpaRkadd_E0fFhKXU')`, by the way. async/await is just nice syntax for promises.
gollark: <@102436520559910912> That's just an anonymous async function, so yes, it won't run if you don't do anything with it.
gollark: To just waste CPU cycles, this has worked for me before when I wanted to do that for some evil reason or other, but it's probably not very sound:```cvolatile long long int i = 0;while (i < [a big number]) { i++; }```
gollark: Oh right, probably.

See also

References
  1. "Mexedrone". New Synthetic Drug Database.
  2. Qian Z, Jia W, Li T, Liu C, Hua Z (February 2017). "Identification and analytical characterization of four synthetic cathinone derivatives iso-4-BMC, β-TH-naphyrone, mexedrone, and 4-MDMC". Drug Testing and Analysis. 9 (2): 274–281. doi:10.1002/dta.1983. PMID 27352812.
  3. Kuś P, Rojkiewicz M, Kusz J, Książek M, Sochanik A (14 May 2019). "Spectroscopic characterization and crystal structures of four hydrochloride cathinones: N-ethyl-2-amino-1-phenylhexan-1-one (hexen, NEH), N-methyl-2-amino-1-(4-methylphenyl)-3-methoxypropan-1-one (mexedrone), N-ethyl-2-amino-1-(3,4-methylenedioxyphenyl)pentan-1-one (ephylone) and N-butyl-2-amino-1-(4-chlorophenyl)propan-1-one (4-chlorobutylcathinone)". Forensic Toxicology. 37 (2): 456–464. doi:10.1007/s11419-019-00477-y.
  4. Roberts L, Ford L, Patel N, Vale JA, Bradberry SM (March 2017). "11 analytically confirmed cases of mexedrone use among polydrug users". Clinical Toxicology. 55 (3): 181–186. doi:10.1080/15563650.2016.1271424. PMID 28075189.
  5. McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, et al. (March 2017). "Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone". Drug Testing and Analysis. 9 (3): 358–368. doi:10.1002/dta.2053. PMC 5336524. PMID 27524685.
  6. "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.
  7. "指定薬物一覧" (PDF) (in Japanese). Ministry of Health, Labour and Welfare.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.