Octodrine

Octodrine (Vaporpac) is a stimulant drug whose pharmacology was studied in a dozen animal studies from the 1940s through the 1970s. These studies found that octodrine can increase blood pressure and cardiac output in animals. The drug was previously approved for use by the FDA as an inhalant (i.e., Vaporpac and Tickle Tackle Inhaler) and in Germany as an oral agent as part of a multicomponent medication (i.e., Ambredin and Ordinal), but is no longer available.[2]

Octodrine

Clinical data
Other names	Ottodrina; Vaporpac; Amidrine; 2-Amino-6-methylheptane; 1,5-Dimethylhexylamine; 6-Methyl-2-heptylamine; 6-Methyl-2-heptanamine[1]
Routes of administration	Oral, inhaled
ATC code	none
Legal status
Legal status	Not currently marketed anywhere, Sometimes sold on the grey market
Identifiers
IUPAC name 6-methylheptan-2-amine
CAS Number	543-82-8^N
PubChem CID	10982
ChemSpider	10517
UNII	3GQ9E911BI
CompTox Dashboard (EPA)	DTXSID8046535
ECHA InfoCard	100.008.047
Chemical and physical data
Formula	C8H19N
Molar mass	129.247 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC(C)CCCC(C)N
InChI InChI=1S/C8H19N/c1-7(2)5-4-6-8(3)9/h7-8H,4-6,9H2,1-3H3 Key:QNIVIMYXGGFTAK-UHFFFAOYSA-N
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Octodrine has also been found as an adulterant in sports supplements.[2]

See also

• 1,3-Dimethylbutylamine
• Methylhexanamine

References

1. CID 10982 from PubChem
2. Cohen PA, Travis JC, Keizers PH, Deuster P, Venhuis BJ (June 2018). "Four experimental stimulants found in sports and weight loss supplements: 2-amino-6-methylheptane (octodrine), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylamylamine (1,3-DMAA) and 1,3-dimethylbutylamine (1,3-DMBA)". Clinical Toxicology. 56 (6): 421–426. doi:10.1080/15563650.2017.1398328. PMID 29115866. S2CID 5193271.