Monatepil

Monatepil is a calcium channel blocker and α₁-adrenergic receptor antagonist used as an antihypertensive.[1]

Monatepil

Names
IUPAC name (RS)-N-(6,11-Dihydrobenzo[c][1]benzothiepin-11-yl)-4-[4-(4-fluorophenyl)-1-piperazinyl]butanamide
Identifiers
CAS Number	103379-03-9^Y
3D model (JSmol)	Interactive image
ChemSpider	54798^N
KEGG	D01171^N
PubChem CID	60810
UNII	N4MMI0J7PW^Y
CompTox Dashboard (EPA)	DTXSID3048811
InChI InChI=1S/C28H30FN3OS/c29-22-11-13-23(14-12-22)32-18-16-31(17-19-32)15-5-10-27(33)30-28-24-7-2-1-6-21(24)20-34-26-9-4-3-8-25(26)28/h1-4,6-9,11-14,28H,5,10,15-20H2,(H,30,33)^N Key: WFNRNNUZFPVBSM-UHFFFAOYSA-N^N InChI=1/C28H30FN3OS/c29-22-11-13-23(14-12-22)32-18-16-31(17-19-32)15-5-10-27(33)30-28-24-7-2-1-6-21(24)20-34-26-9-4-3-8-25(26)28/h1-4,6-9,11-14,28H,5,10,15-20H2,(H,30,33) Key: WFNRNNUZFPVBSM-UHFFFAOYAJ
SMILES C1CN(CCN1CCCC(=O)NC2C3=CC=CC=C3CSC4=CC=CC=C24)C5=CC=C(C=C5)F
Properties
Chemical formula	C28H30FN3OS
Molar mass	475.63 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

References

1. Sugimoto T, Hosoki K, Karasawa T (July 1995). "Relative contribution of alpha 1-adrenoceptor blocking activity to the hypotensive effect of the novel calcium antagonist monatepil". Journal of Cardiovascular Pharmacology. 26 (1): 55–60. doi:10.1097/00005344-199507000-00009. PMID 7564365.