Methdilazine
Methdilazine (Dilosyn, Tacaryl) is a first-generation antihistamine with anticholinergic properties of the phenothiazine class.
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ECHA InfoCard | 100.016.220 |
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Formula | C18H20N2S |
Molar mass | 296.43 g·mol−1 |
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Synthesis
gollark: It may have originally been thought up for some eugenics-y purpose, I don't know, but that does not invalidate it.
gollark: So... general reasoning tests are... racially biased?
gollark: I'm not saying that if you score high on an IQ test then you will magically start doing better or being more intelligent, merely that it is related to some metrics people care about.
gollark: Probably.
gollark: This is, in fact, a conversation about IQ.
See also
References
- L. W. Marsch and R. Peterson, Arzneimittel Forsch., 9, 715 (1959).
- Rani Basu L, Mazumdar K, Dutta N, Karak P, Dastidar S (2005). "Antibacterial property of the antipsychotic agent prochlorperazine, and its synergism with methdilazine". Microbiol Res. 160 (1): 95–100. doi:10.1016/j.micres.2004.10.002. PMID 15782943.
- Chattopadhyay D, Mukherjee T, Pal P, Saha B, Bhadra R (1998). "Altered membrane permeability as the basis of bactericidal action of methdilazine". J Antimicrob Chemother. 42 (1): 83–6. doi:10.1093/jac/42.1.83. PMID 9700532.
- Chattopadhyay D, Dastidar S, Chakrabarty A (1988). "Antimicrobial properties of methdilazine and its synergism with antibiotics and some chemotherapeutic agents". Arzneimittelforschung. 38 (7): 869–72. PMID 2905130.
The ring-contracted analog, methdilazine shows only very weak activity as a tranquilizer; instead, that agent constitutes an important antihistamine.
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