Ethinylestradiol/drospirenone

Ethinylestradiol/drospirenone (EE/DRSP), sold under the brand name Yasmin among others, is a combination of ethinylestradiol (EE), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used as a birth control pill to prevent pregnancy in women.[2][3][4][5] It is also indicated for the treatment of moderate acne, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea (painful menstruation) in women.[3] The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, others).[4][5] A formulation with levomefolic acid (vitamin B9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications.[6][7] EE/DRSP is marketed widely throughout the world.[8]

Ethinylestradiol/drospirenone
Ethinylestradiol
Drospirenone
Combination of
EthinylestradiolEstrogen
DrospirenoneProgestogen; Progestin; Antimineralocorticoid; Antiandrogen
Clinical data
Trade namesWith 30 μg ethinylestradiol: Yasmin, others
With 20 μg ethinylestradiol: Yaz, Yasminelle, others
Other namesEE/DRSP
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601050
License data
Pregnancy
category
    Routes of
    administration    		By mouth
    Drug classEstrogen; Progestin; Progestogen; Antimineralocorticoid; Antiandrogen
    ATC code
    Legal status
    Legal status
    Identifiers
    KEGG

    In 2017, it was the 98th most commonly prescribed medication in the United States, with more than eight million prescriptions.[9][10]

    See also

    References
    1. "Drospirenone / estradiol (Angeliq) Use During Pregnancy". Drugs.com. 6 September 2018. Retrieved 18 March 2020.
    2. https://adisinsight.springer.com/drugs/800007379
    3. https://adisinsight.springer.com/drugs/800017043
    4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021098s028lbl.pdf
    5. "Yaz" (PDF). Retrieved October 31, 2017.
    6. https://adisinsight.springer.com/drugs/800032716
    7. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022532s001lbl.pdf
    8. https://www.drugs.com/international/drospirenone.html
    9. "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
    10. "Drospirenone; Ethinyl Estradiol - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.


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