Amadinone acetate

Amadinone acetate (USAN) (developmental code name RS-2208), also known as 19-norchlormadinone acetate, is a steroidal progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups that was never marketed.[1][2] It is the acetate ester of amadinone, which, similarly, was never marketed.[1][2]

Amadinone acetate

Clinical data
Other names	RS-2208; 19-Norchlormadinone acetate; 6-Chloro-17α-acetoxy-19-norpregna-4,6-diene-3,20-dione
Drug class	Progestogen; Progestogen ester
Identifiers
IUPAC name [(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-13-methyl-3-oxo-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
CAS Number	22304-34-3
PubChem CID	9977739
ChemSpider	8153331
UNII	3E13526FYB
KEGG	D02881
ChEMBL	ChEMBL2104011
CompTox Dashboard (EPA)	DTXSID90176849
Chemical and physical data
Formula	C22H27ClO4
Molar mass	390.90 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)CC[C@H]34)Cl)C)OC(=O)C
InChI InChI=1S/C22H27ClO4/c1-12(24)22(27-13(2)25)9-7-19-17-11-20(23)18-10-14(26)4-5-15(18)16(17)6-8-21(19,22)3/h10-11,15-17,19H,4-9H2,1-3H3/t15-,16-,17-,19+,21+,22+/m1/s1 Key:PSJMYDLEWUWIAN-KYPKCDLESA-N

See also

• Chlormadinone acetate
• List of progestogen esters

References

1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 35–. ISBN 978-1-4757-2085-3.
2. William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 206–. ISBN 978-0-8155-1856-3.