Triclofos

Triclofos is a sedative drug used rarely for treating insomnia.[1]

Triclofos
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.624
Chemical and physical data
FormulaC2H4Cl3O4P
Molar mass229.37 g·mol−1
3D model (JSmol)
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Triclofos is a prodrug which is metabolised in the liver into the active drug trichloroethanol. The half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Triclofos is no longer available in the United States.[2]

Side effects

Side effects may include: headache, rash, dizziness, flatulence, confusion, nightmares, dependence, diarrhoea, constipation, nausea, vomiting, abdominal pain, and ataxia.

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References
  1. Erhorn, Stephen (2007). "Triclofos". xPharm: The Comprehensive Pharmacology Reference. Elsevier. pp. 1–4. ISBN 978-0-08-055232-3. Retrieved 29 February 2020.
  2. "Drugs@FDA: FDA-Approved Drugs". www.accessdata.fda.gov. Retrieved 29 February 2020.


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