Tolufazepam

Tolufazepam is a drug that is a benzodiazepine derivative.[1] Studies have shown tolufazepam to have anticonvulsant and anxiolytic activity in animal subjects,[2] including convulsions elicited by pentylenetetrazol.[3]

Tolufazepam

Identifiers
IUPAC name 7-chloro-5-(2-chlorophenyl)-1-[2-(4-methylphenyl)sulfonylethyl]-3H-1,4-benzodiazepin-2-one
CAS Number	86273-92-9^Y
PubChem CID	65647
ChemSpider	59084^N
UNII	98SR74X50D
CompTox Dashboard (EPA)	DTXSID50235466
Chemical and physical data
Formula	C24H20Cl2N2O3S
Molar mass	487.40 g·mol^−1
3D model (JSmol)	Interactive image
SMILES Clc2ccccc2C(=NCC1=O)c3cc(Cl)ccc3N1CCS(=O)(=O)c(cc4)ccc4C
InChI InChI=1S/C24H20Cl2N2O3S/c1-16-6-9-18(10-7-16)32(30,31)13-12-28-22-11-8-17(25)14-20(22)24(27-15-23(28)29)19-4-2-3-5-21(19)26/h2-11,14H,12-13,15H2,1H3^N Key:FFZOBTGTWSRRMB-UHFFFAOYSA-N^N
^NY (what is this?)  (verify)

See also

• Benzodiazepine

References

1. "List of International Non-Proprietary Names (INNs), Provided for Pharmaceutical Substances by the World Health Organization, Which Are Free of Duty". Official Journal of the European Communities. 23 October 2001. Archived from the original (PDF) on 27 June 2014. Retrieved 7 December 2009.
2. Hrib NJ, Martin LL (1989). Chapter 2. Antianxiety Agents and Anticonvulsants. Annual Reports in Medicinal Chemistry. 24. pp. 11–20. doi:10.1016/s0065-7743(08)60524-2. ISBN 9780120405244.
3. Pérez C, Mondelo N, Stéfano FJ, Lores Arnaiz J (May 1988). "Pharmacological activity of novel alkylsulfonylaryl-1-substituted-1,4-benzodiazepine derivatives". Archives Internationales de Pharmacodynamie et de Therapie. 293: 57–68. PMID 2901826.