Thiobarbital
Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.
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| ECHA InfoCard | 100.000.929  |
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| Formula | C8H12N2O2S |
| Molar mass | 200.259 g·mol−1 |
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Synthesis
It is of note that although the drug can be prepared by the above route (cf e.g. thialbarbital), reaction of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.
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References
- Fischer, E.; Dilthey, A. (1904). "Ueber C-Dialkylbarbitursäuren und über die Ureïde der Dialkylessigsäuren". Justus Liebig's Annalen der Chemie. 335 (3): 334. doi:10.1002/jlac.19043350303.
- Carrington, H. C. (1944). "45. The action of phosphorus pentasulphide on barbituric acids". Journal of the Chemical Society (Resumed): 124. doi:10.1039/JR9440000124.
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