Taniplon

Taniplon is a nonbenzodiazepine anxiolytic drug from the imidazoquinazoline family of drugs.

Taniplon

Clinical data
ATC code	none
Identifiers
IUPAC name 3-(5-methoxy-6,7,8,9-tetrahydroimidazo[1,2-a]quinazolin-2-yl)-5-methyl-1,2,4-oxadiazole
CAS Number	106073-01-2^Y
PubChem CID	3086516
ChemSpider	2343126^N
UNII	OKS0I0BBLP
CompTox Dashboard (EPA)	DTXSID00147500
Chemical and physical data
Formula	C14H15N5O2
Molar mass	285.307 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1=NC(C2=CN3C(N=C(OC)C4=C3CCCC4)=N2)=NO1
InChI InChI=1S/C14H15N5O2/c1-8-15-12(18-21-8)10-7-19-11-6-4-3-5-9(11)13(20-2)17-14(19)16-10/h7H,3-6H2,1-2H3^N Key:OYKONKGGKFFMDV-UHFFFAOYSA-N^N
^NY (what is this?)  (verify)

Taniplon binds strongly to benzodiazepine sites on the GABA_A receptor and has similar anxiolytic effects in animals, but with less sedative or muscle relaxant action.[1]

References

1. Tully WR, Gardner CR, Gillespie RJ, Westwood R (July 1991). "2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors". Journal of Medicinal Chemistry. 34 (7): 2060–7. doi:10.1021/jm00111a021. PMID 1648620.