Demoxepam
Demoxepam[1] is a drug which is a benzodiazepine derivative. It is a metabolite of chlordiazepoxide and has anticonvulsant properties[2][3] and presumably other characteristic benzodiazepine properties.
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| Elimination half-life | 35–40 hours |
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| ECHA InfoCard | 100.012.287  |
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| Formula | C15H11ClN2O2 |
| Molar mass | 286.713 g·mol−1 |
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Synthesis
Demoxepam is also an intermediate in the synthesis of oxazepam; it is also used in one of the syntheses of medazepam. It can be considered directly analogous/synonoymous with the synthesis of chlordiazepoxide, with the exception that instead of methylamine, hydroxide ion is the choice of base; here acid is not used for the cyclodehydration step though.
Demoxepam synthesis: Reeder Earl, Sternbach Leo Henryk, U.S. Patent 3,136,815 (1959 to Hoffmann La Roche).
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gollark: It has `fork`, right?
gollark: Wait, how do you make that work? Do they just not implement the handle interface the same way?
gollark: I use it in PotatOS to add programs to the ROM.
gollark: Yes, I get that, YAFSS has a similar sort of feature.
See also
References
- US Patent 3136815
- "nortetrazepam". psychotropics.dk. 2003. Retrieved 7 December 2009.
- "LIST OF INTERNATIONAL NON-PROPRIETARY NAMES (INNS), PROVIDED FOR PHARMACEUTICAL SUBSTANCES BY THE WORLD HEALTH ORGANIZATION, WHICH ARE FREE OF DUTY" (PDF). Official Journal of the European Communities. eur-lex.europa.eu. 23 October 2001. Retrieved 7 December 2009.
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