Crotylbarbital

Crotylbarbital (Mepertan, Kalipnon, Barotal), also known as crotarbital, is a barbiturate derivative developed by Eli Lilly in the 1930s[1]m It has sedative and hypnotic effects,[2] and was used for the treatment of insomnia until it was replaced by newer alternative drugs with less side effects and lower risk of overdose.

Crotylbarbital

Clinical data
ATC code	none
Identifiers
IUPAC name 5-but-2-enyl-5-ethyl-1,3-diazinane-2,4,6-trione
CAS Number	1952-67-6^Y
PubChem CID	5364821
ChemSpider	4516954^Y
UNII	SXW2HL5JU7
CompTox Dashboard (EPA)	DTXSID90905095
ECHA InfoCard	100.016.162
Chemical and physical data
Formula	C10H14N2O3
Molar mass	210.233 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(CC)C/C=C/C
InChI InChI=1S/C10H14N2O3/c1-3-5-6-10(4-2)7(13)11-9(15)12-8(10)14/h3,5H,4,6H2,1-2H3,(H2,11,12,13,14,15)/b5-3+^Y Key:KNMOHCLEINXVBG-HWKANZROSA-N^Y
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See also

• Barbiturate

References

1. US Patent 2250422
2. Walther T, Meyer FP, Puchta K, Walther H. Effect of an acute dose of crotylbarbital on reaction time and attention testing in healthy human subjects. International Journal of Clinical Pharmacology, Therapy and Toxicology. 1983 Jun;21(6):306-10.