Trional

Trional (Methylsulfonal) is a sedative-hypnotic[1] and anesthetic drug with GABAergic actions. It has similar effects to sulfonal, except it is faster acting.[2]

Trional

Clinical data
ATC code	none
Legal status
Legal status	US: Schedule III
Identifiers
IUPAC name 2,2-bis(ethylsulfonyl)butane
CAS Number	76-20-0^N
PubChem CID	6433
ChemSpider	6193^Y
UNII	217727W28W
CompTox Dashboard (EPA)	DTXSID7046411
ECHA InfoCard	100.000.858
Chemical and physical data
Formula	C8H18O4S2
Molar mass	242.35 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCC(C)(S(=O)(=O)CC)S(=O)(=O)CC
InChI InChI=1S/C8H18O4S2/c1-5-8(4,13(9,10)6-2)14(11,12)7-3/h5-7H2,1-4H3^Y Key:LKACJLUUJRMGFK-UHFFFAOYSA-N^Y
^NY (what is this?)  (verify)

History

Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888.[3]

Appeared in Agatha Christie's "Murder on the Orient Express", "And Then There Were None" and other novels as a sleep inducing sedative, and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as a hypnotic. Sax Rohmer also references trional in his novel Dope.

See also

• Sulfonal
• Tetronal

References

1. (1907). Merck's 1907 Index. N. Y.: Merck & Co., p. 448.
2. Sajous, Charles E. (1896). Annual of the Universal Medical Sciences
   Philadelphia: F. A. Davis, v. 5, p. A-156.
3. Drinkwater, H. (1924). Fifty years of medical progress, 1873-1922.
   New York: The Macmillan Company, p. 40.