Solute carrier organic anion transporter family member 4A1

Solute carrier organic anion transporter family member 4A1 is a protein that in humans is encoded by the SLCO4A1 gene.[5][6]

SLCO4A1
Identifiers
Aliases	SLCO4A1, OATP-E, OATP1, OATP4A1, OATPE, OATPRP1, POAT, SLC21A12, solute carrier organic anion transporter family member 4A1
External IDs	OMIM: 612436 MGI: 1351866 HomoloGene: 9482 GeneCards: SLCO4A1
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.33 Start 62,642,503 bp[1] End 62,685,785 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H4 Start 180,456,245 bp[2] End 180,474,867 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • transporter activity • sodium-independent organic anion transmembrane transporter activity • thyroid hormone transmembrane transporter activity Cellular component • integral component of membrane • cell membrane • membrane • integral component of plasma membrane Biological process • ion transport • sodium-independent organic anion transport • thyroid hormone transport • transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	28231	108115
Ensembl	ENSG00000101187	ENSMUSG00000038963
UniProt	Q96BD0	Q8K078
RefSeq (mRNA)	NM_016354	NM_148933 NM_001355218
RefSeq (protein)	NP_057438	NP_683735 NP_001342147
Location (UCSC)	Chr 20: 62.64 – 62.69 Mb	Chr 2: 180.46 – 180.47 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Solute carrier family

References

1. GRCh38: Ensembl release 89: ENSG00000101187 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038963 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A (Jul 2000). "Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family". Biochem Biophys Res Commun. 273 (1): 251–60. doi:10.1006/bbrc.2000.2922. PMID 10873595.
6. "Entrez Gene: SLCO4A1 solute carrier organic anion transporter family, member 4A1".

Further reading

• Fujiwara K, Adachi H, Nishio T, et al. (2001). "Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner". Endocrinology. 142 (5): 2005–12. doi:10.1210/en.142.5.2005. PMID 11316767.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Pizzagalli F, Varga Z, Huber RD, et al. (2003). "Identification of steroid sulfate transport processes in the human mammary gland". J. Clin. Endocrinol. Metab. 88 (8): 3902–12. doi:10.1210/jc.2003-030174. PMID 12915686.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wang P, Wang JJ, Xiao Y, et al. (2005). "Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface". J. Biol. Chem. 280 (34): 30143–9. doi:10.1074/jbc.M503969200. PMID 15994332.