SLC25A16

Solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 is a protein in humans that is encoded by the SLC25A16 gene. [5]

SLC25A16
Identifiers
Aliases	SLC25A16, D10S105E, GDA, GDC, HGT.1, ML7, hML7, solute carrier family 25 member 16
External IDs	OMIM: 139080 MGI: 1920382 HomoloGene: 21858 GeneCards: SLC25A16
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q21.3 Start 68,477,998 bp[1] End 68,527,523 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B4 Start 62,920,633 bp[2] End 62,946,498 bp[2]
Gene ontology Molecular function • antiporter activity • secondary active transmembrane transporter activity • GO:0022891 transmembrane transporter activity Cellular component • membrane • mitochondrion • mitochondrial inner membrane • integral component of membrane Biological process • transmembrane transport • mitochondrial transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8034	73132
Ensembl	ENSG00000122912	ENSMUSG00000071253
UniProt	P16260	Q8C0K5
RefSeq (mRNA)	NM_152707 NM_001324312 NM_001324313 NM_001324314 NM_001324315 NM_001324317	NM_175194
RefSeq (protein)	NP_001311241 NP_001311242 NP_001311243 NP_001311244 NP_001311246 NP_689920	NP_780403
Location (UCSC)	Chr 10: 68.48 – 68.53 Mb	Chr 10: 62.92 – 62.95 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008].

References

1. GRCh38: Ensembl release 89: ENSG00000122912 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000071253 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16". Retrieved 2012-11-27.

Further reading