Monocarboxylate transporter 6

SLC16A5
Identifiers
Aliases	SLC16A5, MCT5, MCT6, solute carrier family 16 member 5, Monocarboxylate transporter 6
External IDs	OMIM: 603879 MGI: 2443515 HomoloGene: 20985 GeneCards: SLC16A5
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	75,106,162 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	115,474,398 bp[2]
Gene ontology
Molecular function	• symporter activity; • monocarboxylic acid transmembrane transporter activity;
Cellular component	• integral component of membrane; • cell membrane; • integral component of plasma membrane; • membrane;
Biological process	• monocarboxylic acid transport; • transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	9121
	217316
	ENSG00000170190
	ENSMUSG00000045775
	O15375
	G5E8K6
	NM_001271765; NM_004695; NM_001369668
	NM_001080934; NM_001359606; NM_001359608; NM_001359609
	NP_001258694; NP_004686; NP_001356597
	NP_001074403; NP_001346535; NP_001346537; NP_001346538
	Wikidata
View/Edit Human	View/Edit Mouse

Monocarboxylate transporter 6 (MCT6) is a protein in humans that is encoded by the SLC16A5 gene.[5]

This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

References

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