Zinc transporter ZIP2

Zinc transporter ZIP2 is a protein that in humans is encoded by the SLC39A2 gene.[5][6][7]

SLC39A2
Identifiers
Aliases	SLC39A2, 6A1, ETI-1, ZIP-2, ZIP2, solute carrier family 39 member 2
External IDs	OMIM: 612166 MGI: 2684326 HomoloGene: 40957 GeneCards: SLC39A2
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q11.2 Start 20,999,255 bp[1] End 21,001,871 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 C1 Start 51,892,889 bp[2] End 51,896,745 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion transmembrane transporter activity • zinc ion transmembrane transporter activity Cellular component • integral component of membrane • cell membrane • integral component of plasma membrane • membrane • cytoplasmic vesicle Biological process • metal ion transport • zinc II ion transport • ion transport • zinc II ion transmembrane transport • transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	29986	214922
Ensembl	ENSG00000165794	ENSMUSG00000072572
UniProt	Q9NP94	G3X943
RefSeq (mRNA)	NM_014579 NM_001256588	NM_001039676
RefSeq (protein)	NP_001243517 NP_055394	NP_001034765
Location (UCSC)	Chr 14: 21 – 21 Mb	Chr 14: 51.89 – 51.9 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Solute carrier family

References

1. GRCh38: Ensembl release 89: ENSG00000165794 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000072572 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Gaither LA, Eide DJ (Mar 2000). "Functional expression of the human hZIP2 zinc transporter". J Biol Chem. 275 (8): 5560–4. doi:10.1074/jbc.275.8.5560. PMID 10681536.
6. Yamaguchi S (Jun 1995). "[Subtraction cloning of growth arrest inducible genes in normal human epithelial cells]". Kokubyo Gakkai Zasshi. 62 (1): 78–93. PMID 7751801.
7. "Entrez Gene: SLC39A2 solute carrier family 39 (zinc transporter), member 2".

Further reading

• Gong J, Xu J, Bezanilla M, et al. (1999). "Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2". Science. 285 (5433): 1565–9. doi:10.1126/science.285.5433.1565. PMID 10477520.
• Croci C, Brändstatter JH, Enz R (2003). "ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". J. Biol. Chem. 278 (8): 6128–35. doi:10.1074/jbc.M205162200. PMID 12431995.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dufner-Beattie J, Langmade SJ, Wang F, et al. (2004). "Structure, function, and regulation of a subfamily of mouse zinc transporter genes". J. Biol. Chem. 278 (50): 50142–50. doi:10.1074/jbc.M304163200. PMID 14525987.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Desouki MM, Geradts J, Milon B, et al. (2007). "hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands". Mol. Cancer. 6: 37. doi:10.1186/1476-4598-6-37. PMC 1892035. PMID 17550612.