SLC27A3

SLC27A3
Identifiers
Aliases	SLC27A3, ACSVL3, FATP3, VLCS-3, solute carrier family 27 member 3
External IDs	OMIM: 604193 MGI: 1347358 HomoloGene: 11529 GeneCards: SLC27A3
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	153,780,157 bp[1]
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)[2]
End	90,389,938 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• long-chain fatty acid-CoA ligase activity; • nucleotide binding; • ligase activity; • catalytic activity; • very long-chain fatty acid-CoA ligase activity; • GO:0005325 long-chain fatty acid transporter activity; • ATP binding;
Cellular component	• integral component of membrane; • membrane; • mitochondrial membranes; • mitochondrion; • endoplasmic reticulum;
Biological process	• metabolism; • long-chain fatty acid metabolic process; • fatty acid metabolic process; • lipid metabolism; • long-chain fatty acid transport;
	Sources:Amigo / QuickGO
Orthologs
	11000
	26568
	ENSG00000263163; ENSG00000143554
	ENSMUSG00000027932
	Q5K4L6
	O88561
	NM_024330; NM_001317929
	NM_011988; NM_001316688
	NP_001304858; NP_077306
	NP_001303617; NP_036118
	Wikidata
View/Edit Human	View/Edit Mouse

Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the SLC27A3 gene.[5][6]

In melanocytic cells SLC27A3 gene expression may be regulated by MITF.[7]

References

ENSG00000143554 GRCh38: Ensembl release 89: ENSG00000263163, ENSG00000143554 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000027932 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Hirsch D, Stahl A, Lodish HF (Aug 1998). "A family of fatty acid transporters conserved from mycobacterium to man". Proc Natl Acad Sci U S A. 95 (15): 8625–9. doi:10.1073/pnas.95.15.8625. PMC 21126. PMID 9671728.
"Entrez Gene: SLC27A3 solute carrier family 27 (fatty acid transporter), member 3".
Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Pei Z, Fraisl P, Berger J, et al. (2005). "Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells". J. Biol. Chem. 279 (52): 54454–62. doi:10.1074/jbc.M410091200. PMID 15469937.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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