TAAR9

Trace amine-associated receptor 9 is a protein that in humans is encoded by the TAAR9 gene.[5][6]

TAAR9
Identifiers
Aliases	TAAR9, TA3, TAR3, TAR9, TRAR3, trace amine associated receptor 9 (gene/pseudogene), trace amine associated receptor 9
External IDs	OMIM: 608282 MGI: 3527454 HomoloGene: 65286 GeneCards: TAAR9
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q23.2 Start 132,538,290 bp[1] End 132,539,336 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A4 Start 24,108,488 bp[2] End 24,109,534 bp[2]
Gene ontology Molecular function • signal transducer activity • G-protein coupled receptor activity • trace-amine receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • signal transduction • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	134860	503558
Ensembl	ENSG00000237110	ENSMUSG00000037424
UniProt	Q96RI9	Q5QD04
RefSeq (mRNA)	NM_175057	NM_001010831
RefSeq (protein)	NP_778227	NP_001010831
Location (UCSC)	Chr 6: 132.54 – 132.54 Mb	Chr 10: 24.11 – 24.11 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

TAAR9 is a member of a large family of rhodopsin G protein–coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][6] N-Methyl piperidine is a ligand of TAAR9 associated with aversive behavior in mice.[7]

See also

• Trace amine-associated receptor

References

1. GRCh38: Ensembl release 89: ENSG00000237110 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000037424 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (March 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics. 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104.
6. "Entrez Gene: TAAR9 trace amine associated receptor 9".
7. Liberles SD (October 2015). "Trace amine-associated receptors: ligands, neural circuits, and behaviors". Current Opinion in Neurobiology. 34: 1–7. doi:10.1016/j.conb.2015.01.001. PMC 4508243. PMID 25616211.

Further reading

• Borowsky B, Adham N, Jones KA, Raddatz R, Artymyshyn R, Ogozalek KL, et al. (July 2001). "Trace amines: identification of a family of mammalian G protein-coupled receptors". Proceedings of the National Academy of Sciences of the United States of America. 98 (16): 8966–71. doi:10.1073/pnas.151105198. PMC 55357. PMID 11459929.
• Vanti WB, Muglia P, Nguyen T, Cheng R, Kennedy JL, George SR, O'Dowd BF (November 2003). "Discovery of a null mutation in a human trace amine receptor gene". Genomics. 82 (5): 531–6. doi:10.1016/S0888-7543(03)00173-3. PMID 14559210.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.