GPR146

Probable G-protein coupled receptor 146 is a protein that in humans is encoded by the GPR146 gene.[5] It has been identified as a possible receptor for C-peptide.[6]

GPR146
Identifiers
Aliases	GPR146, PGR8, G protein-coupled receptor 146
External IDs	MGI: 1933113 HomoloGene: 36472 GeneCards: GPR146
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p22.3 Start 1,044,546 bp[1] End 1,059,261 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 139,377,697 bp[2] End 139,396,415 bp[2]
Gene ontology Molecular function • signal transducer activity • G-protein coupled receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	115330	80290
Ensembl	ENSG00000164849	ENSMUSG00000044197
UniProt	Q96CH1	Q99LE2
RefSeq (mRNA)	NM_001303473 NM_001303474 NM_138445	NM_001038703 NM_030258
RefSeq (protein)	NP_001290402 NP_001290403 NP_612454	NP_001033792 NP_084534 NP_001349135
Location (UCSC)	Chr 7: 1.04 – 1.06 Mb	Chr 5: 139.38 – 139.4 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000164849 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000044197 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: GPR146 G protein-coupled receptor 146".
6. Yosten GL, Kolar GR, Redlinger LJ, Samson WK (11 July 2013). "Evidence for an interaction between proinsulin C-peptide and GPR146". The Journal of Endocrinology. 218 (2): B1-8. doi:10.1530/JOE-13-0203. PMID 23759446.

Further reading

• Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proceedings of the National Academy of Sciences of the United States of America. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
• Gloriam DE, Schiöth HB, Fredriksson R (Apr 2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochimica et Biophysica Acta (BBA) - General Subjects. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.