GPR62

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.[5][6]

GPR62
Identifiers
Aliases	GPR62, GPCR8, KPG_005, G protein-coupled receptor 62
External IDs	OMIM: 606917 MGI: 3525078 HomoloGene: 50962 GeneCards: GPR62
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.2 Start 51,955,381 bp[1] End 51,957,499 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F1 Start 106,463,962 bp[2] End 106,465,938 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • GO:0001948 protein binding • identical protein binding • arrestin family protein binding Cellular component • integral component of membrane • receptor complex • membrane • cell membrane • endosome • endosome membrane Biological process • signal transduction • G-protein coupled receptor signaling pathway • positive regulation of cAMP-mediated signaling • inositol phosphate-mediated signaling Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	118442	436090
Ensembl	ENSG00000180929	ENSMUSG00000091735
UniProt	Q9BZJ7	Q80UC6
RefSeq (mRNA)	NM_080865	NM_001159652
RefSeq (protein)	NP_543141	NP_001153124
Location (UCSC)	Chr 3: 51.96 – 51.96 Mb	Chr 9: 106.46 – 106.47 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

G protein–coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][6]

References

1. GRCh38: Ensembl release 89: ENSG00000180929 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000091735 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
6. "Entrez Gene: GPR62 G protein-coupled receptor 62".

Further reading

• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.