TAS2R45

Taste receptor type 2 member 45 is a protein that in humans is encoded by the TAS2R45 gene.[2][3]

TAS2R45
Identifiers
Aliases	TAS2R45, GPR59, T2R45, ZG24P, taste 2 receptor member 45
External IDs	OMIM: 613967 GeneCards: TAS2R45
Gene location (Human) Chr. Chromosome 12 (human) Band n/a Start 11,182,986 bp End 11,184,006 bp
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • bitter taste receptor activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • detection of chemical stimulus involved in sensory perception of bitter taste • signal transduction • response to stimulus • sensory perception of taste • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	259291	n/a
Ensembl	ENSG00000261936	n/a
UniProt	P59539	n/a
RefSeq (mRNA)	NM_176886	n/a
RefSeq (protein)	NP_795367	n/a
Location (UCSC)	Chr 12: 11.18 – 11.18 Mb	n/a
PubMed search	[1]	n/a
Wikidata
View/Edit Human

See also

• Taste receptor

References

1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
2. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.
3. "Entrez Gene: TAS2R45 taste receptor, type 2, member 45".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.