Homatropine
Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil).
 | |
| Clinical data | |
|---|---|
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a601006 |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.001.561  |
| Chemical and physical data | |
| Formula | C16H21NO3 |
| Molar mass | 275.348 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
  | |
The related chemical compound homatropine methylbromide (methylhomatropine) is a different medication.
Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt.
Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administration.
Side effects
- Blurred vision
- Sensitivity to light
Contraindications
- Untreated glaucoma
- Myasthenia gravis
- Severe heart failure
- Thyrotoxicosis
gollark: The E5-2670v3 is probably Haswell or so, so the IPC is probably not far off a more recent server.
gollark: So it should be able to under mostly single-thread loads.
gollark: It says it can go up to 3.10GHz.
gollark: Cost ≠ value, as they say.
gollark: "value""Windows"
References
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.