OR9A2

Olfactory receptor 9A2 is a protein that in humans is encoded by the OR9A2 gene.[4]

OR9A2
Identifiers
Aliases	OR9A2, olfactory receptor family 9 subfamily A member 2
External IDs	MGI: 3030293 HomoloGene: 83448 GeneCards: OR9A2
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q34 Start 143,026,158 bp[1] End 143,027,195 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • olfactory receptor activity • signal transducer activity • G-protein coupled receptor activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	135924	258569
Ensembl	ENSG00000273914 ENSG00000179468	n/a
UniProt	Q8NGT5	Q924H8
RefSeq (mRNA)	NM_001001658	NM_146576
RefSeq (protein)	NP_001001658	NP_666787
Location (UCSC)	Chr 7: 143.03 – 143.03 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000179468 GRCh38: Ensembl release 89: ENSG00000273914, ENSG00000179468 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR9A2 olfactory receptor, family 9, subfamily A, member 2".

Further reading

• Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR9A2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.