OR11H6

Olfactory receptor 11H6 is a protein that in humans is encoded by the OR11H6 gene.[4]

OR11H6
Identifiers
AliasesOR11H6, olfactory receptor family 11 subfamily H member 6
External IDsMGI: 3030579 HomoloGene: 27116 GeneCards: OR11H6
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q11.2Start20,223,710 bp[1]
End20,224,702 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

122748

258296

Ensembl

ENSG00000176219

n/a

UniProt

Q8NGC7

Q7TRL9

RefSeq (mRNA)

NM_001004480

NM_146299

RefSeq (protein)

NP_001004480

NP_666411

Location (UCSC)Chr 14: 20.22 – 20.22 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

Ligands
  • Isovaleric acid[5]
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See also

References
  1. GRCh38: Ensembl release 89: ENSG00000176219 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Entrez Gene: OR11H6 olfactory receptor, family 11, subfamily H, member 6".
  5. Menashe I, Abaffy T, Hasin Y, Goshen S, Yahalom V, Luetje CW, Lancet D (October 2007). "Genetic elucidation of human hyperosmia to isovaleric acid". PLoS Biology. 5 (11): e284. doi:10.1371/journal.pbio.0050284. PMC 2043052. PMID 17973576.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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