OR6B1

Olfactory receptor 6B1 is a protein that in humans is encoded by the OR6B1 gene.[4]

OR6B1
Identifiers
Aliases	OR6B1, OR7-3, OR7-9, olfactory receptor family 6 subfamily B member 1
External IDs	MGI: 3030283 HomoloGene: 17485 GeneCards: OR6B1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q35 Start 144,000,320 bp[1] End 144,008,793 bp[1]
Gene ontology Molecular function • olfactory receptor activity • signal transducer activity • G-protein coupled receptor activity Cellular component • membrane • integral component of membrane • cell membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	135946	259067
Ensembl	ENSG00000221813 ENSG00000284939	n/a
UniProt	O95007	n/a
RefSeq (mRNA)	NM_001005281	NM_001356410
RefSeq (protein)	NP_001005281	n/a
Location (UCSC)	Chr 7: 144 – 144.01 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000284939 GRCh38: Ensembl release 89: ENSG00000221813, ENSG00000284939 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR6B1 olfactory receptor, family 6, subfamily B, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR6B1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.