OR4F3

Olfactory receptor 4F3/4F16/4F29 is a protein that in humans is encoded by the OR4F3 gene.[4]

OR4F3
Identifiers
Aliases	OR4F3, olfactory receptor family 4 subfamily F member 3
External IDs	MGI: 3031137 HomoloGene: 88429 GeneCards: OR4F3
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q35.3 Start 181,367,268 bp[1] End 181,368,262 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26683	258397
Ensembl	ENSG00000230178	n/a
UniProt	Q6IEY1	A2AVW1
RefSeq (mRNA)	NM_001005224	NM_146402
RefSeq (protein)	NP_001005224 NP_001005221 NP_001005277	NP_666514
Location (UCSC)	Chr 5: 181.37 – 181.37 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000230178 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR4F3 olfactory receptor, family 4, subfamily F, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4F3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.