OR5L2

Olfactory receptor 5L2 is a protein that in humans is encoded by the OR5L2 gene.[4][5]

OR5L2
Identifiers
Aliases	OR5L2, HSHTPCRX16, HTPCRX16, OR11-153, olfactory receptor family 5 subfamily L member 2
External IDs	MGI: 3030990 HomoloGene: 72031 GeneCards: OR5L2
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 55,827,219 bp[1] End 55,828,154 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • signal transducer activity • olfactory receptor activity • G-protein coupled receptor activity • odorant binding Cellular component • cell membrane • membrane • integral component of membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26338	258814
Ensembl	ENSG00000205030	n/a
UniProt	Q8NGL0	n/a
RefSeq (mRNA)	NM_001004739	NM_146817
RefSeq (protein)	NP_001004739	n/a
Location (UCSC)	Chr 11: 55.83 – 55.83 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000205030 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
5. "Entrez Gene: OR5L2 olfactory receptor, family 5, subfamily L, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5L2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.