OR2AE1

Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.[3]

OR2AE1
Identifiers
Aliases	OR2AE1, OR2AE2, olfactory receptor family 2 subfamily AE member 1
External IDs	HomoloGene: 128272 GeneCards: OR2AE1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 99,875,987 bp[1] End 99,877,057 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81392	n/a
Ensembl	ENSG00000244623	n/a
UniProt	Q8NHA4	n/a
RefSeq (mRNA)	NM_001005276	n/a
RefSeq (protein)	NP_001005276	n/a
Location (UCSC)	Chr 7: 99.88 – 99.88 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000244623 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1".

Further reading

• "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882.

External links

• OR2AE1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.