OR5K1

Olfactory receptor 5K1 is a protein that in humans is encoded by the OR5K1 gene.[4][5]

OR5K1
Identifiers
Aliases	OR5K1, HSHTPCRX10, HTPCRX10, OR3-8, olfactory receptor family 5 subfamily K member 1
External IDs	MGI: 3030006 HomoloGene: 45084 GeneCards: OR5K1
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q11.2 Start 98,463,201 bp[1] End 98,472,924 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26339	259003
Ensembl	ENSG00000232382	n/a
UniProt	Q8NHB7	E9Q8F6
RefSeq (mRNA)	NM_001004736	NM_147001
RefSeq (protein)	NP_001004736	NP_667212
Location (UCSC)	Chr 3: 98.46 – 98.47 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000232382 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
5. "Entrez Gene: OR5K1 olfactory receptor, family 5, subfamily K, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5K1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.