OR2T4

Olfactory receptor 2T4 is a protein that in humans is encoded by the OR2T4 gene.[4]

OR2T4
Identifiers
Aliases	OR2T4, OR1-60, OR2T4Q, olfactory receptor family 2 subfamily T member 4
External IDs	MGI: 3030058 HomoloGene: 133015 GeneCards: OR2T4
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q44 Start 248,361,581 bp[1] End 248,362,627 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	127074	258198
Ensembl	ENSG00000196944 ENSG00000275617 ENSG00000274870	n/a
UniProt	Q8NH00	M9MMJ7
RefSeq (mRNA)	NM_001004696	NM_207695
RefSeq (protein)	NP_001004696	NP_997578
Location (UCSC)	Chr 1: 248.36 – 248.36 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000275617, ENSG00000274870 GRCh38: Ensembl release 89: ENSG00000196944, ENSG00000275617, ENSG00000274870 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR2T4 olfactory receptor, family 2, subfamily T, member 4".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2T4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.