OR4F6

Olfactory receptor 4F6 is a protein that in humans is encoded by the OR4F6 gene.[4]

OR4F6
Identifiers
Aliases	OR4F6, OR15-15, OR4F12, olfactory receptor family 4 subfamily F member 6
External IDs	MGI: 3031144 HomoloGene: 74053 GeneCards: OR4F6
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q26.3 Start 101,803,509 bp[1] End 101,806,887 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • membrane • integral component of membrane • cell membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	390648	258441
Ensembl	ENSG00000184140	n/a
UniProt	Q8NGB9	Q8VF85
RefSeq (mRNA)	NM_001005326	NM_146449
RefSeq (protein)	NP_001005326	NP_666660
Location (UCSC)	Chr 15: 101.8 – 101.81 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000184140 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR4F6 olfactory receptor, family 4, subfamily F, member 6".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4F6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.