OR4Q3

Olfactory receptor 4Q3 is a protein that in humans is encoded by the OR4Q3 gene.[4]

OR4Q3
Identifiers
Aliases	OR4Q3, C14orf13, HSA6, OR14-3, OR4Q4, c14_5008, olfactory receptor family 4 subfamily Q member 3
External IDs	MGI: 3030569 HomoloGene: 71977 GeneCards: OR4Q3
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q11.2 Start 19,743,571 bp[1] End 19,749,469 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	441669	257909
Ensembl	ENSG00000182652	n/a
UniProt	Q8NH05	Q7TRM4
RefSeq (mRNA)	NM_172194	NM_001011754
RefSeq (protein)	NP_751944	NP_001011754
Location (UCSC)	Chr 14: 19.74 – 19.75 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000182652 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR4Q3 olfactory receptor, family 4, subfamily Q, member 3".

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4Q3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.