OR5T2

Olfactory receptor 5T2 is a protein that in humans is encoded by the OR5T2 gene.[4]

OR5T2
Identifiers
Aliases	OR5T2, OR11-177, olfactory receptor family 5 subfamily T member 2
External IDs	MGI: 3030920 HomoloGene: 73975 GeneCards: OR5T2
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 56,231,282 bp[1] End 56,234,255 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity • neurotransmitter receptor activity • G-protein coupled serotonin receptor activity Cellular component • integral component of membrane • cell membrane • membrane • integral component of plasma membrane • dendrite Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • G-protein coupled serotonin receptor signaling pathway • G-protein coupled receptor signaling pathway • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219464	258585
Ensembl	ENSG00000181718 ENSG00000262851	n/a
UniProt	Q8NGG2	Q8VFL9
RefSeq (mRNA)	NM_001004746	NM_146592
RefSeq (protein)	NP_001004746	NP_666803
Location (UCSC)	Chr 11: 56.23 – 56.23 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000262851 GRCh38: Ensembl release 89: ENSG00000181718, ENSG00000262851 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR5T2 olfactory receptor, family 5, subfamily T, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5T2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.