OR10S1

Olfactory receptor 10S1 is a protein that in humans is encoded by the OR10S1 gene.[4]

OR10S1
Identifiers
Aliases	OR10S1, OR11-279, olfactory receptor family 10 subfamily S member 1
External IDs	MGI: 3030816 HomoloGene: 17415 GeneCards: OR10S1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.1 Start 123,976,661 bp[1] End 123,977,781 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219873	258853
Ensembl	ENSG00000196248	n/a
UniProt	Q8NGN2	Q8VGB3
RefSeq (mRNA)	NM_001004474	NM_146854
RefSeq (protein)	NP_001004474	NP_667065
Location (UCSC)	Chr 11: 123.98 – 123.98 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196248 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR10S1 olfactory receptor, family 10, subfamily S, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR10S1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.