OR2W3

Olfactory receptor 2W3 is a protein that in humans is encoded by the OR2W3 gene.[4][5]

OR2W3
Identifiers
Aliases	OR2W3, OR2W3P, OR2W8P, OST718, olfactory receptor family 2 subfamily W member 3
External IDs	OMIM: 616729 MGI: 3030156 HomoloGene: 19876 GeneCards: OR2W3
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q44 Start 247,895,587 bp[1] End 247,896,531 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • olfactory receptor activity Cellular component • membrane • cell membrane • integral component of membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	343171	404346
Ensembl	ENSG00000238243	n/a
UniProt	Q7Z3T1	Q5NCC8
RefSeq (mRNA)	NM_001001957	NM_207693
RefSeq (protein)	NP_001001957	NP_997576
Location (UCSC)	Chr 1: 247.9 – 247.9 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000238243 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
5. "Entrez Gene: OR2W3 olfactory receptor, family 2, subfamily W, member 3".

Further reading

• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.

External links

• OR2W3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.