OR2F2

Olfactory receptor 2F2 is a protein that in humans is encoded by the OR2F2 gene.[4]

OR2F2
Identifiers
Aliases	OR2F2, OR7-1, olfactory receptor family 2 subfamily F member 2
External IDs	MGI: 3030286 HomoloGene: 128141 GeneCards: OR2F2
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q35 Start 143,935,166 bp[1] End 143,936,279 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	135948	258207
Ensembl	ENSG00000221910 ENSG00000284965	n/a
UniProt	O95006	Q7TRV8
RefSeq (mRNA)	NM_001004685	NM_001011869
RefSeq (protein)	NP_001004685	NP_001011869
Location (UCSC)	Chr 7: 143.94 – 143.94 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000284965 GRCh38: Ensembl release 89: ENSG00000221910, ENSG00000284965 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR2F2 olfactory receptor, family 2, subfamily F, member 2".

Further reading

• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2F2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.