OR5V1

Olfactory receptor 5V1 is a protein that in humans is encoded by the OR5V1 gene.[4]

OR5V1
Identifiers
Aliases	OR5V1, 6M1-21, hs6M1-21, olfactory receptor family 5 subfamily V member 1
External IDs	MGI: 2177493 HomoloGene: 73968 GeneCards: OR5V1
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.1 Start 29,353,749 bp[1] End 29,431,967 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81696	258325
Ensembl	ENSG00000112461 ENSG00000227137 ENSG00000243441 ENSG00000243729 ENSG00000233046 ENSG00000230742 ENSG00000240130 ENSG00000242289	n/a
UniProt	Q9UGF6	A2RT31
RefSeq (mRNA)	NM_030876	NM_146328
RefSeq (protein)	NP_110503	NP_666440
Location (UCSC)	Chr 6: 29.35 – 29.43 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000227137, ENSG00000243441, ENSG00000243729, ENSG00000233046, ENSG00000230742, ENSG00000240130, ENSG00000242289 GRCh38: Ensembl release 89: ENSG00000112461, ENSG00000227137, ENSG00000243441, ENSG00000243729, ENSG00000233046, ENSG00000230742, ENSG00000240130, ENSG00000242289 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR5V1 olfactory receptor, family 5, subfamily V, member 1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5V1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.