OR5B3

Olfactory receptor 5B3 is a protein that in humans is encoded by the OR5B3 gene.[4]

OR5B3
Identifiers
Aliases	OR5B3, OR11-239, OR5B13, OST129, olfactory receptor family 5 subfamily B member 3
External IDs	MGI: 3031297 HomoloGene: 133886 GeneCards: OR5B3
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 58,402,464 bp[1] End 58,406,874 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	441608	258120
Ensembl	ENSG00000172769	n/a
UniProt	Q8NH48	Q7TQR3
RefSeq (mRNA)	NM_001005469	NM_001011840
RefSeq (protein)	NP_001005469	NP_001011840
Location (UCSC)	Chr 11: 58.4 – 58.41 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172769 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR5B3 olfactory receptor, family 5, subfamily B, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5B3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.