OR13F1

Olfactory receptor 13F1 is a protein that in humans is encoded by the OR13F1 gene.[4]

OR13F1
Identifiers
Aliases	OR13F1, OR9-6, olfactory receptor family 13 subfamily F member 1
External IDs	MGI: 3030109 HomoloGene: 17418 GeneCards: OR13F1
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q31.1 Start 104,504,263 bp[1] End 104,505,222 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity • adrenergic receptor activity • dopamine neurotransmitter receptor activity, coupled via Gi/Go • dopamine binding Cellular component • integral component of membrane • cell membrane • integral component of plasma membrane • membrane • synaptic vesicle membrane • intracellular Biological process • adenylate cyclase-activating adrenergic receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • synaptic transmission, dopaminergic • negative regulation of adenylate cyclase activity • adenylate cyclase-inhibiting dopamine receptor signaling pathway • response to toxic substance • regulation of dopamine secretion • response to drug • regulation of potassium ion transport • behavioral response to cocaine • behavioral response to ethanol • negative regulation of cytosolic calcium ion concentration • negative regulation of synaptic transmission, glutamatergic • phospholipase C-activating dopamine receptor signaling pathway • negative regulation of voltage-gated calcium channel activity • G-protein coupled receptor signaling pathway • adrenergic receptor signaling pathway • adenylate cyclase-modulating G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	138805	258857
Ensembl	ENSG00000186881	n/a
UniProt	Q8NGS4	Q7TS18
RefSeq (mRNA)	NM_001004485	NM_146858
RefSeq (protein)	NP_001004485	NP_667069
Location (UCSC)	Chr 9: 104.5 – 104.51 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000186881 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR13F1 olfactory receptor, family 13, subfamily F, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.

External links

• OR13F1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.