OR8K3

Olfactory receptor, family 8, subfamily K, member 3, also known as OR8K3, is a protein which in humans is encoded by the OR8K3 gene.[4]

OR8K3
Identifiers
Aliases	OR8K3, OR11-181, olfactory receptor family 8 subfamily K member 3 (gene/pseudogene)
External IDs	MGI: 3030888 HomoloGene: 133882 GeneCards: OR8K3
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 56,315,144 bp[1] End 56,320,639 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219473	259021
Ensembl	ENSG00000262755 ENSG00000280314	n/a
UniProt	Q8NH51	Q8VGS7
RefSeq (mRNA)	NM_001005202	NM_147019
RefSeq (protein)	NP_001005202	NP_667230
Location (UCSC)	Chr 11: 56.32 – 56.32 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

References

1. ENSG00000280314 GRCh38: Ensembl release 89: ENSG00000262755, ENSG00000280314 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR8K3 olfactory receptor, family 8, subfamily K, member 3".; This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR8K3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)