OR5AS1

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene.[4]

OR5AS1
Identifiers
Aliases	OR5AS1, OR11-168, olfactory receptor family 5 subfamily AS member 1
External IDs	MGI: 3030945 HomoloGene: 74238 GeneCards: OR5AS1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 56,027,654 bp[1] End 56,038,191 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219447	258586
Ensembl	ENSG00000181785	n/a
UniProt	Q8N127	Q7TR55
RefSeq (mRNA)	NM_001001921	NM_146593
RefSeq (protein)	NP_001001921	NP_666804
Location (UCSC)	Chr 11: 56.03 – 56.04 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein–coupled receptors (GPCR) arising from single coding-exon genes.

Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

References

1. GRCh38: Ensembl release 89: ENSG00000181785 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR5AS1 olfactory receptor, family 5, subfamily AS, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5AS1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.