Quipazine

Quipazine is a piperazine drug used in scientific research. It is a moderately selective serotonin receptor receptor agonist, binding to a range of different serotonin receptors, but particularly to the 5-HT_2A[1] and 5-HT₃.[2]

Quipazine

Clinical data
ATC code	none
Identifiers
IUPAC name 2-piperazin-1-ylquinoline
CAS Number	4774-24-7^Y
PubChem CID	5011
IUPHAR/BPS	173
ChemSpider	4836^N
UNII	4WCY05C0SJ
ChEMBL	ChEMBL18772^N
CompTox Dashboard (EPA)	DTXSID3046952
ECHA InfoCard	100.164.885
Chemical and physical data
Formula	C13H15N3
Molar mass	213.284 g·mol^−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCN1)C2=NC3=CC=CC=C3C=C2
InChI InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2^N Key:XRXDAJYKGWNHTQ-UHFFFAOYSA-N^N
^NY (what is this?)  (verify)

See also

• Substituted piperazine

References

1. Smith RL, Barrett RJ, Sanders-Bush E (November 1995). "Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor". The Journal of Pharmacology and Experimental Therapeutics. 275 (2): 1050–7. PMID 7473132.
2. Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, et al. (February 1998). "Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives". Journal of Medicinal Chemistry. 41 (5): 728–41. doi:10.1021/jm970645i. PMID 9513601.