Tropanserin
Tropanserin (INN; MDL-72,422) is a drug which acts as a potent and selective 5-HT3 receptor antagonist.[1] It was investigated in clinical trials for the treatment of migraine in the 1980s but was never marketed.[2]
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| Formula | C17H23NO2 |
| Molar mass | 273.376 g·mol−1 |
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Synthesis
Tropanserin can be prepared by the reaction of tropine with 3,5-dimethylbenzoyl chloride.
Tropanserin synthesis[3]
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gollark: A 2.5"/SATA one like what you had before is probably fine and would be cheaper.
gollark: You can get faster NVMe ones, but cheaper ones will just be SATA like a 2.5" SSD. I don't think NVMe disks are currently worth it for most people anyway.
gollark: M.2 drives are not actually always faster.
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See also
References
- King FD, Jones BJ, Sanger GJ (22 October 1993). 5-Hydroxytryptamine-3 Receptor Antagonists. CRC Press. p. 244. ISBN 978-0-8493-5463-2. Retrieved 6 May 2012.
- Johnson G (1 August 1987). "Recent Advances in Migraine Research". In Bailey DM (ed.). Annual Reports in Medicinal Chemistry. 22. Academic Press. p. 44. doi:10.1016/S0065-7743(08)61153-7. ISBN 978-0-08-058366-2.
- US 4563465, Fozard JR, Gittos MW, "Treatment of migraine with substituted tropyl benzoate derivatives", issued 7 January 1986, assigned to Merrell Dow Pharma
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