STK40

Serine/threonine-protein kinase 40 is an enzyme that in humans is encoded by the STK40 gene.[5]

STK40
Identifiers
Aliases	STK40, SHIK, SgK495, serine/threonine kinase 40
External IDs	OMIM: 609437 MGI: 1921428 HomoloGene: 12542 GeneCards: STK40
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p34.3 Start 36,339,624 bp[1] End 36,385,896 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D2.2 Start 126,103,957 bp[2] End 126,141,029 bp[2]
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase activity • protein serine/threonine kinase activity • GO:0001948 protein binding • ATP binding • kinase activity Cellular component • cell nucleus • nucleoplasm • cytoplasm • cytosol Biological process • glycogen metabolic process • regulation of gene expression • protein phosphorylation • lung alveolus development • respiratory system process • negative regulation of apoptotic process • regulation of MAPK cascade • lung morphogenesis • phosphorylation • multicellular organism growth • lung development Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	83931	74178
Ensembl	ENSG00000196182	ENSMUSG00000042608
UniProt	Q8N2I9	Q7TNL3
RefSeq (mRNA)	NM_032017 NM_001282546 NM_001282547	NM_001145827 NM_028800
RefSeq (protein)	NP_001269475 NP_001269476 NP_114406	NP_001139299 NP_083076
Location (UCSC)	Chr 1: 36.34 – 36.39 Mb	Chr 4: 126.1 – 126.14 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000196182 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042608 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: STK40 serine/threonine kinase 40".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Huang J, Teng L, Liu T, et al. (2003). "Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappaB activation and p53-induced transcription". Biochem. Biophys. Res. Commun. 309 (4): 774–8. doi:10.1016/j.bbrc.2003.08.069. PMID 13679039.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.