Cephem

Cephems are a sub-group of β-lactam antibiotics including cephalosporins and cephamycins.[1] It is one of the most common 4-membered ring heterocycle.[2]

Core structure of the cephalosporins.

Core structure of the cephamycins.

References

"medscape.com". Retrieved 2008-12-29.
Vitaku, E., D. T. Smith and J. T. Njardarson (2014). "Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals". Journal of Medicinal Chemistry. 57: 10257–10274. doi:10.1021/jm501100b. PMID 25255204.CS1 maint: uses authors parameter (link)

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[Medscape-1] "medscape.com". Retrieved 2008-12-29.

[2] Vitaku, E., D. T. Smith and J. T. Njardarson (2014). "Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals". Journal of Medicinal Chemistry. 57: 10257–10274. doi:10.1021/jm501100b. PMID 25255204.CS1 maint: uses authors parameter (link)