Cefsulodin
Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by Takeda Pharmaceutical Company in 1977.[1]
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| Formula | C22H21N4O8S2+ |
| Molar mass | 533.55 g·mol−1 |
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TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985.[2]
Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms.[3] This agar is most often used in water and beverage testing.
Susceptibility data
The following represents MIC susceptibility data for various P. aeruginosa strains:[4]
- Pseudomonas aeruginosa PA13 (resistant strain): 32 μg/ml
- Pseudomonas aeruginosa (wild-type, susceptible): 4 - 8 μg/ml
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References
- TOKU-E Technical Application Sheet
- "Lupron Is First Abbott-Takeda Product to Reach U.S. Market". Pink Sheet. 15 April 1985.
- "BAM Media M35: Cefsulodin-Irgasan Novobiocin Agar or Yersinia Selective Agar". Retrieved 2 September 2012.
- http://antibiotics.toku-e.com/antimicrobial_474.html
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