Biapenem

Biapenem
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	IV
ATC code	J01DH05 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (4R,5S,6S)-3-(6,7-dihydro-5H- pyrazolo[1,2-a][1,2,4]triazol-8- ium-6-ylsulfanyl)- 6-(1-hydroxyethyl)- 4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylate;
CAS Number	120410-24-4 ;
PubChem CID	71339;
ChemSpider	64442 ;
UNII	YR5U3L9ZH1;
ChEBI	CHEBI:3089 ;
ChEMBL	ChEMBL285347 ;
CompTox Dashboard (EPA)	DTXSID5046435 ;
Chemical and physical data
Formula	C15H18N4O4S
Molar mass	350.39 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])C(C)O;
	InChI InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1 ; Key:MRMBZHPJVKCOMA-YJFSRANCSA-N ;
	(verify)

Biapenem (INN) is a carbapenem antibiotic. It has in vitro activity against anaerobes.[1] 1-β-methyl-carbapenem antibiotic. Approved in Japan in 2001.

References

Aldridge KE, Morice N, Schiro DD (April 1994). "In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes". Antimicrob. Agents Chemother. 38 (4): 889–93. doi:10.1128/aac.38.4.889. PMC 284564. PMID 8031067.

External links

(in Japanese) Omegacin

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[pmid8031067-1] Aldridge KE, Morice N, Schiro DD (April 1994). "In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes". Antimicrob. Agents Chemother. 38 (4): 889–93. doi:10.1128/aac.38.4.889. PMC 284564. PMID 8031067.