Cefpirome

Cefpirome
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01DE02 (WHO) ;
Identifiers
	IUPAC name 1-{[(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-5H,6H,7H-cyclopenta[b]pyridin-1-ium;
CAS Number	84957-29-9 ;
PubChem CID	6917674;
ChemSpider	23089536 ;
UNII	S72Q2F09HY;
KEGG	D07649 ;
ChEMBL	ChEMBL2106076 ;
CompTox Dashboard (EPA)	DTXSID2048244 ;
Chemical and physical data
Formula	C22H22N6O5S2
Molar mass	514.58 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CON=C(c1csc(n1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[n+]4cccc5c4CCC5)C(=O)[O-];
	InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m1/s1 ; Key:DKOQGJHPHLTOJR-XECLGWKCSA-N ;
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Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, and Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria.

Spectrum of bacterial susceptibility and resistance

Bacteroides fragilis, enterococci, Pseudomonas spp. and staphylococci are resistant to cefpirome sulfate, and some Haemophilus spp. and pneumococci have developed resistance to it to varying degrees.[1]

gollark: ~~Scratch~~

gollark: Constraint calculus. Constraints in Haskell—which are the mechanism for reaching into the typeclass prolog system—are structurally typed. This gives a very simple form of subtyping relationship which lets you assemble complex constraints from simpler ones. The entire mtl library is based on this idea.

gollark: "ITWAT <@485027179286102018> Is Totally Wrong About Tau.

gollark: πIWTTπ Is Worse Than Tau.

gollark: ∆IKOAGL∆ Is Kind Of A Greek Letter

References

"Cefpirome Sulfate spectrum of bacterial susceptibility and Resistance" (PDF). Archived from the original (PDF) on 3 March 2016. Retrieved 10 April 2012.

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[1] "Cefpirome Sulfate spectrum of bacterial susceptibility and Resistance" (PDF). Archived from the original (PDF) on 3 March 2016. Retrieved 10 April 2012.